Cardiac 12/15 lipoxygenase–induced inflammation is involved in heart failure

To identify a novel target for the treatment of heart failure, we examined gene expression in the failing heart. Among the genes analyzed, Alox15 encoding the protein 12/15 lipoxygenase (LOX) was markedly up-regulated in heart failure. To determine whether increased expression of 12/15-LOX causes he...

Descripción completa

Detalles Bibliográficos
Autores principales: Kayama, Yosuke, Minamino, Tohru, Toko, Haruhiro, Sakamoto, Masaya, Shimizu, Ippei, Takahashi, Hidehisa, Okada, Sho, Tateno, Kaoru, Moriya, Junji, Yokoyama, Masataka, Nojima, Aika, Yoshimura, Michihiro, Egashira, Kensuke, Aburatani, Hiroyuki, Komuro, Issei
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2009
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2715088/
https://www.ncbi.nlm.nih.gov/pubmed/19546247
http://dx.doi.org/10.1084/jem.20082596

Ejemplares similares

Ejemplares similares