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Identification of the UBP1 Locus as a Critical Blood Pressure Determinant Using a Combination of Mouse and Human Genetics
Hypertension is a major health problem of largely unknown genetic origins. To identify new genes responsible for hypertension, genetic analysis of recombinant inbred strains of mice followed by human association studies might prove powerful and was exploited in our current study. Using a set of 27 r...
Autores principales: | Koutnikova, Hana, Laakso, Markku, Lu, Lu, Combe, Roy, Paananen, Jussi, Kuulasmaa, Teemu, Kuusisto, Johanna, Häring, Hans-Ulrich, Hansen, Torben, Pedersen, Oluf, Smith, Ulf, Hanefeld, Markolf, Williams, Robert W., Auwerx, Johan |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2715105/ https://www.ncbi.nlm.nih.gov/pubmed/19662162 http://dx.doi.org/10.1371/journal.pgen.1000591 |
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