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The Wiskott-Aldrich syndrome protein is required for iNKT cell maturation and function
The Wiskott-Aldrich syndrome (WAS) protein (WASp) is a regulator of actin cytoskeleton in hematopoietic cells. Mutations of the WASp gene cause WAS. Although WASp is involved in various immune cell functions, its role in invariant natural killer T (iNKT) cells has never been investigated. Defects of...
Autores principales: | Locci, Michela, Draghici, Elena, Marangoni, Francesco, Bosticardo, Marita, Catucci, Marco, Aiuti, Alessandro, Cancrini, Caterina, Marodi, Laszlo, Espanol, Teresa, Bredius, Robbert G.M., Thrasher, Adrian J., Schulz, Ansgar, Litzman, Jiri, Roncarolo, Maria Grazia, Casorati, Giulia, Dellabona, Paolo, Villa, Anna |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2715111/ https://www.ncbi.nlm.nih.gov/pubmed/19307326 http://dx.doi.org/10.1084/jem.20081773 |
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