Thymic progenitor homing and lymphocyte homeostasis are linked via S1P-controlled expression of thymic P-selectin/CCL25

Thymic T cell progenitor (TCP) importation is a periodic, gated event that is dependent on the expression of functional P-selectin ligands on TCPs. Occupancy of intrathymic TCP niches is believed to negatively regulate TCP importation, but the nature of this feedback mechanism is not yet resolved. W...

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Detalles Bibliográficos
Autores principales: Gossens, Klaus, Naus, Silvia, Corbel, Stephane Y., Lin, Shujun, Rossi, Fabio M.V., Kast, Jürgen, Ziltener, Hermann J.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2009
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2715120/
https://www.ncbi.nlm.nih.gov/pubmed/19289576
http://dx.doi.org/10.1084/jem.20082502

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