Cargando…

Drug inhibition of HDAC3 and epigenetic control of differentiation in Apicomplexa parasites

Plasmodium and Toxoplasma are parasites of major medical importance that belong to the Apicomplexa phylum of protozoa. These parasites transform into various stages during their life cycle and express a specific set of proteins at each stage. Although little is yet known of how gene expression is co...

Descripción completa

Detalles Bibliográficos
Autores principales:	Bougdour, Alexandre, Maubon, Danièle, Baldacci, Patricia, Ortet, Philippe, Bastien, Olivier, Bouillon, Anthony, Barale, Jean-Christophe, Pelloux, Hervé, Ménard, Robert, Hakimi, Mohamed-Ali
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2009
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2715132/ https://www.ncbi.nlm.nih.gov/pubmed/19349466 http://dx.doi.org/10.1084/jem.20082826

Ejemplares similares

Mobilome of Apicomplexa Parasites
por: Rodriguez, Matias, et al.
Publicado: (2022)

The flexibility of Apicomplexa parasites in lipid metabolism
por: Shunmugam, Serena, et al.
Publicado: (2022)

Building the Perfect Parasite: Cell Division in Apicomplexa
por: Striepen, Boris, et al.
Publicado: (2007)

Leishmania killicki Imported from Tunisian Desert
por: Maubon, Danièle, et al.
Publicado: (2009)

Migration of Apicomplexa Across Biological Barriers: The Toxoplasma and Plasmodium Rides
por: Tardieux, Isabelle, et al.
Publicado: (2008)

Revealing parasite influence in metabolic pathways in Apicomplexa infected patients
por: Xu, Tao, et al.
Publicado: (2010)

Modifications at K31 on the lateral surface of histone H4 contribute to genome structure and expression in apicomplexan parasites
por: Sindikubwabo, Fabien, et al.
Publicado: (2017)

Full-parasites: database of full-length cDNAs of apicomplexa parasites, 2010 update
por: Tuda, Josef, et al.
Publicado: (2011)

Efficacy of eleven antimicrobials against a gregarine parasite (Apicomplexa: Protozoa)
por: Johny, Shajahan, et al.
Publicado: (2007)

Sophisticated Adaptations of Gregarina cuneata (Apicomplexa) Feeding Stages for Epicellular Parasitism
por: Valigurová, Andrea
Publicado: (2012)

A Complex Small RNA Repertoire Is Generated by a Plant/Fungal-Like Machinery and Effected by a Metazoan-Like Argonaute in the Single-Cell Human Parasite Toxoplasma gondii
por: Braun, Laurence, et al.
Publicado: (2010)

Identifying Novel Cell Cycle Proteins in Apicomplexa Parasites through Co-Expression Decision Analysis
por: Butler, Carrie L., et al.
Publicado: (2014)

Where Does the Alignment Score Distribution Shape Come from?
por: Ortet, Philippe, et al.
Publicado: (2010)

Large, rapidly evolving gene families are at the forefront of host–parasite interactions in Apicomplexa
por: REID, ADAM J
Publicado: (2015)

Sexual Development in Non-Human Parasitic Apicomplexa: Just Biology or Targets for Control?
por: Cruz-Bustos, Teresa, et al.
Publicado: (2021)

Changes in K(+) Concentration as a Signaling Mechanism in the Apicomplexa Parasites Plasmodium and Toxoplasma
por: Santos, Benedito M. Dos, et al.
Publicado: (2023)

Specific Targeting of Plant and Apicomplexa Parasite Tubulin through Differential Screening Using In Silico and Assay-Based Approaches
por: Soleilhac, Emmanuelle, et al.
Publicado: (2018)

A Systematic Review of Apicomplexa Looking into Epigenetic Pathways and the Opportunity for Novel Therapies
por: Brandão, Yara de Oliveira, et al.
Publicado: (2023)

Structural Basis for the Subversion of MAP Kinase Signaling by an Intrinsically Disordered Parasite Secreted Agonist
por: Pellegrini, Erika, et al.
Publicado: (2017)

Patterns of host-parasite associations between marine meiofaunal flatworms (Platyhelminthes) and rhytidocystids (Apicomplexa)
por: Van Steenkiste, Niels W. L., et al.
Publicado: (2023)

The Toxoplasma effector TEEGR promotes parasite persistence by modulating NF-kB signalling via EZH2
por: Braun, Laurence, et al.
Publicado: (2019)

Targeting Toxoplasma gondii CPSF3 as a new approach to control toxoplasmosis
por: Palencia, Andrés, et al.
Publicado: (2017)

The 18S rRNA genes of Haemoproteus (Haemosporida, Apicomplexa) parasites from European songbirds with remarks on improved parasite diagnostics
por: Harl, Josef, et al.
Publicado: (2023)

Target Identification of an Antimalarial Oxaborole Identifies AN13762 as an Alternative Chemotype for Targeting CPSF3 in Apicomplexan Parasites
por: Bellini, Valeria, et al.
Publicado: (2020)

Parasites and malignancies, a review, with emphasis on digestive cancer induced by Cryptosporidium parvum (Alveolata: Apicomplexa)
por: Benamrouz, S., et al.
Publicado: (2012)

Cryptosporidium and Toxoplasma Parasites Are Inhibited by a Benzoxaborole Targeting Leucyl-tRNA Synthetase
por: Palencia, Andrés, et al.
Publicado: (2016)

A MORC-driven transcriptional switch controls Toxoplasma developmental trajectories and sexual commitment
por: Farhat, Dayana C., et al.
Publicado: (2020)

Profiles of low complexity regions in Apicomplexa
por: Battistuzzi, Fabia U., et al.
Publicado: (2016)

Characterization of mRNA polyadenylation in the apicomplexa
por: Stevens, Ashley T., et al.
Publicado: (2018)

Editorial: Parasites in the Tropic—A New Paradigm Shift
por: Nissapatorn, Veeranoot, et al.
Publicado: (2017)

A configuration space of homologous proteins conserving mutual information and allowing a phylogeny inference based on pair-wise Z-score probabilities
por: Bastien, Olivier, et al.
Publicado: (2005)

Identification of a New Rhoptry Neck Complex RON9/RON10 in the Apicomplexa Parasite Toxoplasma gondii
por: Lamarque, Mauld H., et al.
Publicado: (2012)

Do apicomplexan parasites hijack the host cell microRNA pathway for their intracellular development?
por: Hakimi, Mohamed-Ali, et al.
Publicado: (2010)

Computational Design of Protein-Based Inhibitors of Plasmodium vivax Subtilisin-Like 1 Protease
por: Bastianelli, Giacomo, et al.
Publicado: (2014)

A Tiny Change Makes a Big Difference in the Anti-Parasitic Activities of an HDAC Inhibitor
por: Loeuillet, Corinne, et al.
Publicado: (2019)

Identification of a Divergent Environmental DNA Sequence Clade Using the Phylogeny of Gregarine Parasites (Apicomplexa) from Crustacean Hosts
por: Rueckert, Sonja, et al.
Publicado: (2011)

Characterization of a Toxoplasma effector uncovers an alternative GSK3/β-catenin-regulatory pathway of inflammation
por: He, Huan, et al.
Publicado: (2018)

A Toxoplasma dense granule protein, GRA24, modulates the early immune response to infection by promoting a direct and sustained host p38 MAPK activation
por: Braun, Laurence, et al.
Publicado: (2013)

Computational Reverse-Engineering of a Spider-Venom Derived Peptide Active Against Plasmodium falciparum SUB1
por: Bastianelli, Giacomo, et al.
Publicado: (2011)

Structural and evolutionary divergence of eukaryotic protein kinases in Apicomplexa
por: Talevich, Eric, et al.
Publicado: (2011)

Cannot write session to /tmp/vufind_sessions/sess_cj6vba79srfnt7ui7vsbjk3adp