Cargando…
A Condensation-Ordering Mechanism in Nanoparticle-Catalyzed Peptide Aggregation
Nanoparticles introduced in living cells are capable of strongly promoting the aggregation of peptides and proteins. We use here molecular dynamics simulations to characterise in detail the process by which nanoparticle surfaces catalyse the self-assembly of peptides into fibrillar structures. The s...
Autores principales: | Auer, Stefan, Trovato, Antonio, Vendruscolo, Michele |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2009
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2715216/ https://www.ncbi.nlm.nih.gov/pubmed/19680431 http://dx.doi.org/10.1371/journal.pcbi.1000458 |
Ejemplares similares
-
A Generic Mechanism of Emergence of Amyloid Protofilaments from Disordered Oligomeric Aggregates
por: Auer, Stefan, et al.
Publicado: (2008) -
Sequence-based
Prediction of the Cellular Toxicity
Associated with Amyloid Aggregation within Protein Condensates
por: Horvath, Attila, et al.
Publicado: (2022) -
Enhanced Ribozyme‐Catalyzed Recombination and Oligonucleotide Assembly in Peptide‐RNA Condensates
por: Le Vay, Kristian, et al.
Publicado: (2021) -
Protein condensation diseases: therapeutic opportunities
por: Vendruscolo, Michele, et al.
Publicado: (2022) -
Spontaneous nucleation and fast aggregate-dependent proliferation of α-synuclein aggregates within liquid condensates at neutral pH
por: Dada, Samuel T., et al.
Publicado: (2023)