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R-loops do not accumulate in transcription-defective hpr1-101 mutants: implications for the functional role of THO/TREX
To get further insight into the effect that THO/TREX and R-loops have in transcription-associated recombination and transcription, we analyzed the ability to form R-loops of hpr1-101, a THO mutation that impairs transcription and mRNP biogenesis without triggering hyper-recombination. Human AID, a c...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2009
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2715242/ https://www.ncbi.nlm.nih.gov/pubmed/19451165 http://dx.doi.org/10.1093/nar/gkp385 |