High-throughput sequence-based epigenomic analysis of Alu repeats in human cerebellum

DNA methylation, the only known covalent modification of mammalian DNA, occurs primarily in CpG dinucleotides. 51% of CpGs in the human genome reside within repeats, and 25% within Alu elements. Despite that, no method has been reported for large-scale ascertainment of CpG methylation in repeats. He...

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Detalles Bibliográficos
Autores principales: Xie, Hehuang, Wang, Min, Bonaldo, Maria de F., Smith, Christina, Rajaram, Veena, Goldman, Stewart, Tomita, Tadanori, Soares, Marcelo B.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2009
Materias:
Gene Regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2715246/
https://www.ncbi.nlm.nih.gov/pubmed/19458156
http://dx.doi.org/10.1093/nar/gkp393

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2715246/
https://www.ncbi.nlm.nih.gov/pubmed/19458156
http://dx.doi.org/10.1093/nar/gkp393

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