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High-throughput sequence-based epigenomic analysis of Alu repeats in human cerebellum
DNA methylation, the only known covalent modification of mammalian DNA, occurs primarily in CpG dinucleotides. 51% of CpGs in the human genome reside within repeats, and 25% within Alu elements. Despite that, no method has been reported for large-scale ascertainment of CpG methylation in repeats. He...
Autores principales: | Xie, Hehuang, Wang, Min, Bonaldo, Maria de F., Smith, Christina, Rajaram, Veena, Goldman, Stewart, Tomita, Tadanori, Soares, Marcelo B. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2715246/ https://www.ncbi.nlm.nih.gov/pubmed/19458156 http://dx.doi.org/10.1093/nar/gkp393 |
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