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Light-activated RNA interference using double-stranded siRNA precursors modified using a remarkable regiospecificity of diazo-based photolabile groups
Diazo-based precursors of photolabile groups have been used extensively for modifying nucleic acids, with the intention of toggling biological processes with light. These processes include transcription, translation and RNA interference. In these cases, the photolabile groups have been typically dep...
Autores principales: | Shah, Samit, Jain, Piyush K., Kala, Ashish, Karunakaran, Dipu, Friedman, Simon H. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2715251/ https://www.ncbi.nlm.nih.gov/pubmed/19477960 http://dx.doi.org/10.1093/nar/gkp415 |
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