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Processing of thymine glycol in a clustered DNA damage site: mutagenic or cytotoxic

Localized clustering of damage is a hallmark of certain DNA-damaging agents, particularly ionizing radiation. The potential for genetic change arising from the effects of clustered damage sites containing combinations of AP sites, 8-oxo-7,8-dihydroguanine (8-oxoG) or 5,6-dihydrothymine is high. To d...

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Detalles Bibliográficos
Autores principales:	Bellon, Sophie, Shikazono, Naoya, Cunniffe, Siobhan, Lomax, Martine, O’Neill, Peter
Formato:	Texto
Lenguaje:	English
Publicado:	Oxford University Press 2009
Materias:	Genome Integrity, Repair and Replication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2715253/ https://www.ncbi.nlm.nih.gov/pubmed/19468043 http://dx.doi.org/10.1093/nar/gkp422

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