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Role of ERK/MAPK in endothelin receptor signaling in human aortic smooth muscle cells
BACKGROUND: Endothelin-1 (ET-1) is a potent vasoactive peptide, which induces vasoconstriction and proliferation in vascular smooth muscle cells (VSMCs) through activation of endothelin type A (ET(A)) and type B (ET(B)) receptors. The extracellular signal-regulated kinase 1 and 2 (ERK1/2) mitogen-ac...
Autores principales: | , , |
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Formato: | Texto |
Lenguaje: | English |
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BioMed Central
2009
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2715373/ https://www.ncbi.nlm.nih.gov/pubmed/19575782 http://dx.doi.org/10.1186/1471-2121-10-52 |