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The Cellular Prion Protein Interacts with the Tissue Non-Specific Alkaline Phosphatase in Membrane Microdomains of Bioaminergic Neuronal Cells

BACKGROUND: The cellular prion protein, PrP(C), is GPI anchored and abundant in lipid rafts. The absolute requirement of PrP(C) in neurodegeneration associated to prion diseases is well established. However, the function of this ubiquitous protein is still puzzling. Our previous work using the 1C11...

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Detalles Bibliográficos
Autores principales: Ermonval, Myriam, Baudry, Anne, Baychelier, Florence, Pradines, Elodie, Pietri, Mathéa, Oda, Kimimitsu, Schneider, Benoît, Mouillet-Richard, Sophie, Launay, Jean-Marie, Kellermann, Odile
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2715859/
https://www.ncbi.nlm.nih.gov/pubmed/19652718
http://dx.doi.org/10.1371/journal.pone.0006497