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Dopamine Modulates Persistent Synaptic Activity and Enhances the Signal-to-Noise Ratio in the Prefrontal Cortex
BACKGROUND: The importance of dopamine (DA) for prefrontal cortical (PFC) cognitive functions is widely recognized, but its mechanisms of action remain controversial. DA is thought to increase signal gain in active networks according to an inverted U dose-response curve, and these effects may depend...
Autores principales: | Kroener, Sven, Chandler, L. Judson, Phillips, Paul E. M., Seamans, Jeremy K. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2715878/ https://www.ncbi.nlm.nih.gov/pubmed/19654866 http://dx.doi.org/10.1371/journal.pone.0006507 |
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