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Novel ENU-Induced Point Mutation in Scavenger Receptor Class B, Member 1, Results in Liver Specific Loss of SCARB1 Protein

Cardiovascular disease (CVD) is the largest cause of premature death in human populations throughout the world. Circulating plasma lipid levels, specifically high levels of LDL or low levels of HDL, are predictive of susceptibility to CVD. The scavenger receptor class B member 1 (SCARB1) is the prim...

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Detalles Bibliográficos
Autores principales: Stylianou, Ioannis M., Svenson, Karen L., VanOrman, Sara K., Langle, Yanina, Millar, John S., Paigen, Beverly, Rader, Daniel J.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2715880/
https://www.ncbi.nlm.nih.gov/pubmed/19654867
http://dx.doi.org/10.1371/journal.pone.0006521