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Altered proteolytic events in experimental autoimmune encephalomyelitis discovered by iTRAQ shotgun proteomics analysis of spinal cord

BACKGROUND: Abnormal activation of protease activities during experimental autoimmune encephalomyelitis (EAE) in rats, a rodent model of multiple sclerosis, have been implicated in either the direct destruction of myelin components or the intracellular signal transduction pathways that lead to lymph...

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Detalles Bibliográficos
Autores principales: Jain, Mohit Raja, Bian, Shengjie, Liu, Tong, Hu, Jun, Elkabes, Stella, Li, Hong
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2716311/
https://www.ncbi.nlm.nih.gov/pubmed/19607715
http://dx.doi.org/10.1186/1477-5956-7-25

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