The radiosensitizer 2-benzoyl-3-phenyl-6,7-dichloroquinoxaline 1,4-dioxide induces DNA damage in EMT-6 mammary carcinoma cells

BACKGROUND: DCQ (2-benzoyl-3-phenyl-6,7-dichloroquinoxaline 1,4-dioxide), a synthetic quinoxaline 1,4-dioxide, enhances the cytotoxic effect of ionizing radiation (IR) in vivo and in vitro. We sought to clarify whether increased radiation-induced DNA damage, decreased rate of damage repair, and the...

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Detalles Bibliográficos
Autores principales: Haykal, Joelle, Geara, Fady, Haddadin, Makhluf J, Smith, Colin A, Gali-Muhtasib, Hala
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2716350/
https://www.ncbi.nlm.nih.gov/pubmed/19594955
http://dx.doi.org/10.1186/1748-717X-4-25

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