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Analysis of cyclins A, B1, D1 and E in breast cancer in relation to tumour grade and other prognostic factors

BACKGROUND: The cell cycle is promoted by activation of cyclin dependent kinases (Cdks), which are regulated positively by cyclins and negatively by Cdk inhibitors. Proliferation of carcinoma is associated with altered regulation of the cell cycle. Little is known on the combined alterations of cycl...

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Detalles Bibliográficos
Autores principales: Boström, Pia, Söderström, Mirva, Palokangas, Tuire, Vahlberg, Tero, Collan, Yrjö, Carpen, Olli, Hirsimäki, Pirkko
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2716358/
https://www.ncbi.nlm.nih.gov/pubmed/19615042
http://dx.doi.org/10.1186/1756-0500-2-140