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Exaptation of an ancient Alu short interspersed element provides a highly conserved vitamin D-mediated innate immune response in humans and primates

BACKGROUND: About 45% of the human genome is comprised of mobile transposable elements or "junk DNA". The exaptation or co-option of these elements to provide important cellular functions is hypothesized to have played a powerful force in evolution; however, proven examples are rare. An an...

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Detalles Bibliográficos
Autores principales: Gombart, Adrian F, Saito, Tsuyako, Koeffler, H Phillip
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2716374/
https://www.ncbi.nlm.nih.gov/pubmed/19607716
http://dx.doi.org/10.1186/1471-2164-10-321