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The role of YY1 in reduced HP1α gene expression in invasive human breast cancer cells
INTRODUCTION: Heterochromatin protein 1 (HP1) associates with chromatin by binding to histone H3 and contributes to gene silencing. There are three isoforms of HP1 in mammals: HP1α, β, and γ. Studies have shown that the level of HP1α is reduced in invasive human breast cancer cell lines such as MDA-...
Autores principales: | Lieberthal, Jason G, Kaminsky, Marissa, Parkhurst, Christopher N, Tanese, Naoko |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2716511/ https://www.ncbi.nlm.nih.gov/pubmed/19566924 http://dx.doi.org/10.1186/bcr2329 |
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