Cargando…

Safety and Efficacy of Dihydroartemisinin-Piperaquine in Falciparum Malaria: A Prospective Multi-Centre Individual Patient Data Analysis

BACKGROUND: The fixed dose antimalarial combination of dihydroartemisinin-piperaquine (DP) is a promising new artemisinin-based combination therapy (ACT). We present an individual patient data analysis of efficacy and tolerability in acute uncomplicated falciparum malaria, from seven published rando...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zwang, Julien, Ashley, Elizabeth A., Karema, Corine, D'Alessandro, Umberto, Smithuis, Frank, Dorsey, Grant, Janssens, Bart, Mayxay, Mayfong, Newton, Paul, Singhasivanon, Pratap, Stepniewska, Kasia, White, Nicholas J., Nosten, François
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2009
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2716525/ https://www.ncbi.nlm.nih.gov/pubmed/19649267 http://dx.doi.org/10.1371/journal.pone.0006358

Ejemplares similares

A Phase III, Randomized, Non-Inferiority Trial to Assess the Efficacy and Safety of Dihydroartemisinin-Piperaquine in Comparison with Artesunate-Mefloquine in Patients with Uncomplicated Plasmodium falciparum Malaria in Southern Laos
por: Mayxay, Mayfong, et al.
Publicado: (2010)

Comparison of plasma, venous and capillary blood levels of piperaquine in patients with uncomplicated falciparum malaria
por: Ashley, Elizabeth A., et al.
Publicado: (2010)

An Open-Label, Randomised Study of Dihydroartemisinin-Piperaquine Versus Artesunate-Mefloquine for Falciparum Malaria in Asia
por: Valecha, Neena, et al.
Publicado: (2010)

Correction: An Open-Label, Randomised Study of Dihydroartemisinin-Piperaquine Versus Artesunate-Mefloquine for Falciparum Malaria in Asia
por: Valecha, Neena, et al.
Publicado: (2010)

Correction: An Open-Label, Randomised Study of Dihydroartemisinin-Piperaquine Versus Artesunate-Mefloquine for Falciparum Malaria in Asia
por: Valecha, Neena, et al.
Publicado: (2010)

Dihydroartemisinin‐piperaquine for treating uncomplicated Plasmodium falciparum malaria
por: Zani, Babalwa, et al.
Publicado: (2014)

Dihydroartemisinin-Piperaquine Versus Chloroquine in the Treatment of Plasmodium vivax Malaria in Thailand: A Randomized Controlled Trial
por: Phyo, Aung Pyae, et al.
Publicado: (2011)

Treatment Failure of Dihydroartemisinin/Piperaquine for Plasmodium falciparum Malaria, Vietnam
por: Phuc, Bui Quang, et al.
Publicado: (2017)

Electrocardiographic effect of artemisinin-piperaquine, dihydroartemisinin-piperaquine, and artemether-lumefantrine treatment in falciparum malaria patients
por: Wu, Wanting, et al.
Publicado: (2021)

A Randomised Controlled Trial to Assess the Efficacy of Dihydroartemisinin-Piperaquine for the Treatment of Uncomplicated Falciparum Malaria in Peru
por: Grande, Tanilu, et al.
Publicado: (2007)

Therapeutic efficacies of artemether-lumefantrine and dihydroartemisinin-piperaquine for the treatment of uncomplicated Plasmodium falciparum and chloroquine and dihydroartemisinin-piperaquine for uncomplicated Plasmodium vivax infection in Ethiopia
por: Assefa, Ashenafi, et al.
Publicado: (2022)

Safety and efficacy of dihydroartemisinin-piperaquine versus artemether-lumefantrine in the treatment of uncomplicated Plasmodium falciparum malaria in Zambian children
por: Nambozi, Michael, et al.
Publicado: (2011)

Blackwater fever in an uncomplicated Plasmodium falciparum patient treated with dihydroartemisinin-piperaquine
por: Lon, Chanthap, et al.
Publicado: (2014)

Dihydroartemisinin-Piperaquine Treatment of Multidrug Resistant Falciparum and Vivax Malaria in Pregnancy
por: Poespoprodjo, Jeanne Rini, et al.
Publicado: (2014)

Rapid decline in the susceptibility of Plasmodium falciparum to dihydroartemisinin–piperaquine in the south of Vietnam
por: Thanh, Ngo Viet, et al.
Publicado: (2017)

The relationship between the haemoglobin concentration and the haematocrit in Plasmodium falciparum malaria
por: Lee, Sue J, et al.
Publicado: (2008)

Correction: Therapeutic efficacies of artemether-lumefantrine and dihydroartemisinin-piperaquine for the treatment of uncomplicated Plasmodium falciparum and chloroquine and dihydroartemisinin-piperaquine for uncomplicated Plasmodium vivax infection in Ethiopia
por: Assefa, Ashenaf, et al.
Publicado: (2023)

Haemoglobin changes and risk of anaemia following treatment for uncomplicated falciparum malaria in sub-Saharan Africa
por: Zwang, Julien, et al.
Publicado: (2017)

Prediction of Improved Antimalarial Chemoprevention with Weekly Dosing of Dihydroartemisinin-Piperaquine
por: Permala, Jesmin, et al.
Publicado: (2017)

Artemether-Lumefantrine versus Dihydroartemisinin-Piperaquine for Treatment of Malaria: A Randomized Trial
por: Kamya, Moses R, et al.
Publicado: (2007)

Efficacy and Day 7 Plasma Piperaquine Concentrations in African Children Treated for Uncomplicated Malaria with Dihydroartemisinin-Piperaquine
por: Zongo, Issaka, et al.
Publicado: (2014)

Plasmodium falciparum clearance in clinical studies of artesunate-amodiaquine and comparator treatments in sub-Saharan Africa, 1999–2009
por: Zwang, Julien, et al.
Publicado: (2014)

Dihydroartemisinin-piperaquine versus chloroquine to treat vivax malaria in Afghanistan: an open randomized, non-inferiority, trial
por: Awab, Ghulam Rahim, et al.
Publicado: (2010)

Variable piperaquine exposure significantly impacts protective efficacy of monthly dihydroartemisinin-piperaquine for the prevention of malaria in Ugandan children
por: Sundell, Kerstin, et al.
Publicado: (2015)

Artemether-Lumefantrine and Dihydroartemisinin-Piperaquine Exert Inverse Selective Pressure on Plasmodium Falciparum Drug Sensitivity-Associated Haplotypes in Uganda
por: Taylor, Aimee R., et al.
Publicado: (2016)

Failure of dihydroartemisinin plus piperaquine treatment of falciparum malaria by under-dosing in an overweight patient
por: Roseau, Jean Baptiste, et al.
Publicado: (2016)

The dynamic of asymptomatic Plasmodium falciparum infections following mass drug administrations with dihydroarteminisin–piperaquine plus a single low dose of primaquine in Savannakhet Province, Laos
por: Pongvongsa, Tiengkham, et al.
Publicado: (2018)

Efficacy of Quinine, Artemether-Lumefantrine and Dihydroartemisinin-Piperaquine as Rescue Treatment for Uncomplicated Malaria in Ugandan Children
por: Yeka, Adoke, et al.
Publicado: (2013)

Optimal dosing of dihydroartemisinin-piperaquine for seasonal malaria chemoprevention in young children
por: Chotsiri, Palang, et al.
Publicado: (2019)

High therapeutic efficacy of artemether–lumefantrine and dihydroartemisinin–piperaquine for the treatment of uncomplicated falciparum malaria in Somalia
por: Warsame, Marian, et al.
Publicado: (2019)

Adherence to Mass Drug Administration with Dihydroartemisinin–Piperaquine and Plasmodium falciparum Clearance in Southern Province, Zambia
por: Finn, Timothy P., et al.
Publicado: (2020)

Case Report: Autoimmune Hemolysis Anemia After Dihydroartemisinin and Piperaquine for Uncomplicated Plasmodium falciparum Malaria
por: Louvois, Marion, et al.
Publicado: (2022)

Mass drug administrations with dihydroartemisinin-piperaquine and single low dose primaquine to eliminate Plasmodium falciparum have only a transient impact on Plasmodium vivax: Findings from randomised controlled trials
por: Phommasone, Koukeo, et al.
Publicado: (2020)

Comparing changes in haematologic parameters occurring in patients included in randomized controlled trials of artesunate-amodiaquine vs single and combination treatments of uncomplicated falciparum in sub-Saharan Africa
por: Zwang, Julien, et al.
Publicado: (2012)

Sequential Open-Label Study of the Safety, Tolerability, and Pharmacokinetic Interactions between Dihydroartemisinin-Piperaquine and Mefloquine in Healthy Thai Adults
por: Hanboonkunupakarn, Borimas, et al.
Publicado: (2019)

Therapeutic efficacy and safety of dihydroartemisinin-piperaquine versus artesunate-mefloquine in uncomplicated Plasmodium falciparum malaria in India
por: Gargano, Nicola, et al.
Publicado: (2012)

Failure of dihydroartemisinin-piperaquine treatment of uncomplicated Plasmodium falciparum malaria in a traveller coming from Ethiopia
por: Gobbi, Federico, et al.
Publicado: (2016)

Prevalence of Plasmodium falciparum gametocytaemia in asymptomatic school children before and after treatment with dihydroartemisinin-piperaquine (DP)
por: Dinko, Bismarck, et al.
Publicado: (2023)

Molecular markers of dihydroartemisinin-piperaquine resistance in northwestern Thailand
por: Win, Khine Nwe, et al.
Publicado: (2022)

Artesunate/dihydroartemisinin pharmacokinetics in acute falciparum malaria in pregnancy: absorption, bioavailability, disposition and disease effects
por: McGready, Rose, et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_tpsjios5hn3v6c0ju7aq129fas