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Angiotensin II Type 1 Receptor Blockers Reduce Urinary Angiotensinogen Excretion and the Levels of Urinary Markers of Oxidative Stress and Inflammation in Patients with Type 2 Diabetic Nephropathy

OBJECTIVE: To demonstrate that the administration of an angiotensin (Ang) II type 1 receptor (AT1R) blocker (ARB) inhibits the vicious cycle of high glucose (HG)-reactive oxygen species (ROS)-angiotensinogen (AGT)-Ang II-AT1R-ROS by suppressing ROSs and inflammation, thus ameliorating diabetic nephr...

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Detalles Bibliográficos
Autores principales:	Ogawa, Susumu, Kobori, Hiroyuki, Ohashi, Naro, Urushihara, Maki, Nishiyama, Akira, Mori, Takefumi, Ishizuka, Tsuneo, Nako, Kazuhiro, Ito, Sadayoshi
Formato:	Texto
Lenguaje:	English
Publicado:	Libertas Academica 2009
Materias:	Short Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2716676/ https://www.ncbi.nlm.nih.gov/pubmed/19652765

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