Uncertainty Analysis of Drug Concentration in Pharmaceutical Mixtures

Using a Taylor expansion to first order, a novel method was developed to calculate the uncertainty of drug concentration in pharmaceutical dosage forms. The method allows, in principle, calculation of the maximum potential error in drug concentration in a mixture composed of an infinite number of in...

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Detalles Bibliográficos
Autor principal: Savva, Michalakis
Formato: Texto
Lenguaje:English
Publicado: Libertas Academica 2008
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2716773/
https://www.ncbi.nlm.nih.gov/pubmed/19690634
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author Savva, Michalakis
author_facet Savva, Michalakis
author_sort Savva, Michalakis
collection PubMed
description Using a Taylor expansion to first order, a novel method was developed to calculate the uncertainty of drug concentration in pharmaceutical dosage forms. The method allows, in principle, calculation of the maximum potential error in drug concentration in a mixture composed of an infinite number of ingredients that are measured on multiple balances of variable sensitivity requirements.
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spelling pubmed-27167732009-08-18 Uncertainty Analysis of Drug Concentration in Pharmaceutical Mixtures Savva, Michalakis Anal Chem Insights Original Research Using a Taylor expansion to first order, a novel method was developed to calculate the uncertainty of drug concentration in pharmaceutical dosage forms. The method allows, in principle, calculation of the maximum potential error in drug concentration in a mixture composed of an infinite number of ingredients that are measured on multiple balances of variable sensitivity requirements. Libertas Academica 2008-06-03 /pmc/articles/PMC2716773/ /pubmed/19690634 Text en Copyright © 2006 The authors. http://creativecommons.org/licenses/by/3.0 This article is an open-access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).
spellingShingle Original Research
Savva, Michalakis
Uncertainty Analysis of Drug Concentration in Pharmaceutical Mixtures
title Uncertainty Analysis of Drug Concentration in Pharmaceutical Mixtures
title_full Uncertainty Analysis of Drug Concentration in Pharmaceutical Mixtures
title_fullStr Uncertainty Analysis of Drug Concentration in Pharmaceutical Mixtures
title_full_unstemmed Uncertainty Analysis of Drug Concentration in Pharmaceutical Mixtures
title_short Uncertainty Analysis of Drug Concentration in Pharmaceutical Mixtures
title_sort uncertainty analysis of drug concentration in pharmaceutical mixtures
topic Original Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2716773/
https://www.ncbi.nlm.nih.gov/pubmed/19690634
work_keys_str_mv AT savvamichalakis uncertaintyanalysisofdrugconcentrationinpharmaceuticalmixtures

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