Role of (99m)Tc-(V)DMSA in Detecting Tumor Cell Proliferation

Pentavalent technetium-99m dimercaptosuccinic acid ((99m)Tc-(V)DMSA) is a tumor-seeking agent which was introduced to evaluate, image, and manage many types of cancers. In this review, the beginning of, and the most recent applications of using this agent was appraised. The relation with tumor cell...

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Detalles Bibliográficos
Autor principal: Al-Saeedi, Fatma
Formato: Texto
Lenguaje:English
Publicado: Libertas Academica 2007
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2716817/
https://www.ncbi.nlm.nih.gov/pubmed/19662181
Descripción
Sumario:Pentavalent technetium-99m dimercaptosuccinic acid ((99m)Tc-(V)DMSA) is a tumor-seeking agent which was introduced to evaluate, image, and manage many types of cancers. In this review, the beginning of, and the most recent applications of using this agent was appraised. The relation with tumor cell detection and proliferation was reported and several mechanisms of uptake of (99m)Tc-(V)DMSA in tumor cells are described.

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