Human Neurospheres as Three-Dimensional Cellular Systems for Developmental Neurotoxicity Testing

BACKGROUND: Developmental neurotoxicity (DNT) of environmental chemicals is a serious threat to human health. Current DNT testing guidelines propose investigations in rodents, which require large numbers of animals. With regard to the “3 Rs” (reduction, replacement, and refinement) of animal testing...

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Detalles Bibliográficos
Autores principales: Moors, Michaela, Rockel, Thomas Dino, Abel, Josef, Cline, Jason E., Gassmann, Kathrin, Schreiber, Timm, Schuwald, Janette, Weinmann, Nicole, Fritsche, Ellen
Formato: Texto
Lenguaje:English
Publicado: National Institute of Environmental Health Sciences 2009
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2717141/
https://www.ncbi.nlm.nih.gov/pubmed/19654924
http://dx.doi.org/10.1289/ehp.0800207

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2717141/
https://www.ncbi.nlm.nih.gov/pubmed/19654924
http://dx.doi.org/10.1289/ehp.0800207

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