Cargando…

Enhanced Survival of Spiral Ganglion Cells After Cessation of Treatment with Brain-Derived Neurotrophic Factor in Deafened Guinea Pigs

Exogenous delivery of neurotrophic factors into the cochlea of deafened animals rescues spiral ganglion cells (SGCs) from degeneration. To be clinically relevant for human cochlear implant candidates, the protective effect of neurotrophins should persist after cessation of treatment and the treated...

Descripción completa

Detalles Bibliográficos
Autores principales:	Agterberg, Martijn J. H., Versnel, Huib, van Dijk, Lotte M., de Groot, John C. M. J., Klis, Sjaak F. L.
Formato:	Texto
Lenguaje:	English
Publicado:	Springer-Verlag 2009
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2717388/ https://www.ncbi.nlm.nih.gov/pubmed/19365690 http://dx.doi.org/10.1007/s10162-009-0170-2

Ejemplares similares

Changes in the Electrically Evoked Compound Action Potential over time After Implantation and Subsequent Deafening in Guinea Pigs
por: Ramekers, Dyan, et al.
Publicado: (2022)

mTOR Signaling in BDNF-Treated Guinea Pigs after Ototoxic Deafening
por: Tisi, Annamaria, et al.
Publicado: (2022)

Combined brain-derived neurotrophic factor and neurotrophin-3 treatment is preferred over either one separately in the preservation of the auditory nerve in deafened guinea pigs
por: Vink, Henk A., et al.
Publicado: (2022)

Ouabain Does Not Induce Selective Spiral Ganglion Cell Degeneration in Guinea Pigs
por: Schomann, Timo, et al.
Publicado: (2018)

No Protective Effects of Hair Cells or Supporting Cells in Ototoxically Deafened Guinea Pigs upon Administration of BDNF
por: Tisi, Annamaria, et al.
Publicado: (2021)

BDNF Outperforms TrkB Agonist 7,8,3′-THF in Preserving the Auditory Nerve in Deafened Guinea Pigs
por: Vink, Henk A., et al.
Publicado: (2020)

Towards Clinical Application of Neurotrophic Factors to the Auditory Nerve; Assessment of Safety and Efficacy by a Systematic Review of Neurotrophic Treatments in Humans
por: Bezdjian, Aren, et al.
Publicado: (2016)

Spontaneous Behavior in Noise and Silence: A Possible New Measure to Assess Tinnitus in Guinea Pigs
por: Heeringa, Amarins N., et al.
Publicado: (2014)

Structural changes in the inner ear over time studied in the experimentally deafened guinea pig
por: Fransson, Anette, et al.
Publicado: (2016)

Differential Effects of AAV.BDNF and AAV.Ntf3 in the Deafened Adult Guinea Pig Ear
por: Budenz, Cameron L., et al.
Publicado: (2015)

Dendrogenin A and B two new steroidal alkaloids increasing neural responsiveness in the deafened guinea pig
por: Fransson, Anette, et al.
Publicado: (2015)

Acute effects of cochleostomy and electrode-array insertion on compound action potentials in normal-hearing guinea pigs
por: Jwair, Saad, et al.
Publicado: (2023)

Mimic Cochlear Implant Surgery-Induced Cochlear Infection Fails to Further Damage Auditory Pathway in Deafened Guinea Pigs
por: Han, Zhao, et al.
Publicado: (2018)

Transplantation of human adipose tissue-derived stem cells for repair of injured spiral ganglion neurons in deaf guinea pigs
por: Jang, Sujeong, et al.
Publicado: (2016)

The Deafened Man and Hearing Aids
por: Love, James Kerr
Publicado: (1937)

The Three-Dimensional Culture System with Matrigel and Neurotrophic Factors Preserves the Structure and Function of Spiral Ganglion Neuron In Vitro
por: Sun, Gaoying, et al.
Publicado: (2016)

Functional Pattern of Increasing Concentrations of Brain-Derived Neurotrophic Factor in Spiral Ganglion: Implications for Research on Cochlear Implants
por: Ramku, Emina, et al.
Publicado: (2017)

Potentiation of Brain-Derived Neurotrophic Factor-Induced Protection of Spiral Ganglion Neurons by C3 Exoenzyme/Rho Inhibitor
por: Harre, Jennifer, et al.
Publicado: (2021)

Purification of Fibroblasts From the Spiral Ganglion
por: Anacker, Annett, et al.
Publicado: (2022)

Corrigendum: Potentiation of brain-derived neurotrophic factor-induced protection of spiral ganglion neurons by C3 exoenzyme/Rho inhibitor
por: Harre, Jennifer, et al.
Publicado: (2022)

Primary Cultivation and Identification of Vascular Smooth Muscle Cells from the Spiral Modiolar Artery of Guinea Pigs
por: Xiao, Jingjie, et al.
Publicado: (2018)

GUINEA PIGS
por: Riggs, Shannon M.
Publicado: (2009)

Audiovisual Temporal Processing in Postlingually Deafened Adults with Cochlear Implants
por: Butera, Iliza M., et al.
Publicado: (2018)

Similarities in the Biophysical Properties of Spiral-Ganglion and Vestibular-Ganglion Neurons in Neonatal Rats
por: Kalluri, Radha
Publicado: (2021)

Long-term delivery of brain-derived neurotrophic factor (BDNF) from nanoporous silica nanoparticles improves the survival of spiral ganglion neurons in vitro
por: Schmidt, Nadeschda, et al.
Publicado: (2018)

Deafening Silence: The Lack of Structured Patient Symptoms in Clinical Documentation of Angina
por: Bradley, Steven M.
Publicado: (2019)

Mechanism and Prevention of Spiral Ganglion Neuron Degeneration in the Cochlea
por: Zhang, Li, et al.
Publicado: (2022)

Implicit Processing of Pitch in Postlingually Deafened Cochlear Implant Users
por: Tillmann, Barbara, et al.
Publicado: (2019)

Guinea Pigs
Publicado: (2013)

SUBMICROSCOPIC CHANGES OF THE SYNAPSE AFTER NERVE SECTION IN THE ACOUSTIC GANGLION OF THE GUINEA PIG. AN ELECTRON MICROSCOPE STUDY
por: De Robertis, Eduardo
Publicado: (1956)

Comparison of Methods for the Histological Evaluation of Odontocete Spiral Ganglion Cells
por: Ramírez, Tania, et al.
Publicado: (2020)

Generation of a Spiral Ganglion Neuron Degeneration Mouse Model
por: Hu, Zhengqing, et al.
Publicado: (2021)

Effect of Immunophilin Inhibitors on Cochlear Fibroblasts and Spiral Ganglion Cells
por: Goblet, Madeleine, et al.
Publicado: (2023)

Is cochlear implantation a good treatment method for profoundly deafened elderly?
por: Lachowska, Magdalena, et al.
Publicado: (2013)

The molecular etiology of deafness and auditory performance in the postlingually deafened cochlear implantees
por: Lee, Sang-Yeon, et al.
Publicado: (2020)

The effect of cochlear implantation on autonomy, participation and work in postlingually deafened adults: a scoping review
por: Nijmeijer, Hugo G. B., et al.
Publicado: (2020)

TOXEMIA OF PREGNANCY IN THE GUINEA PIG
por: Foley, Edward J.
Publicado: (1942)

Cytotoxicity of guinea-pig lymphoid cells against guinea-pig hepatoma cells in tissue culture.
por: Andjargholi, M., et al.
Publicado: (1977)

The Biology of the guinea pig /
Publicado: (1976)

The Microscope or the Guinea-Pig?
por: Greene, Harry S. N.
Publicado: (1946)

Cannot write session to /tmp/vufind_sessions/sess_9to06bp0l820d4jv9u0o5kog4k