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Characterization of highly stable liposomal and immunoliposomal formulations of vincristine and vinblastine

PURPOSE: Liposome and immunoliposome formulations of two vinca alkaloids, vincristine and vinblastine, were prepared using intraliposomal triethylammonium sucroseoctasulfate and examined for their ability to stabilize the drug for targeted drug delivery in vivo. METHODS: The pharmacokinetics of both...

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Detalles Bibliográficos
Autores principales:	Noble, Charles O., Guo, Zexiong, Hayes, Mark E., Marks, James D., Park, John W., Benz, Christopher C., Kirpotin, Dmitri B., Drummond, Daryl C.
Formato:	Texto
Lenguaje:	English
Publicado:	Springer-Verlag 2009
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2717390/ https://www.ncbi.nlm.nih.gov/pubmed/19184019 http://dx.doi.org/10.1007/s00280-008-0923-3

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