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Exploring the unknown: assumptions about allelic architecture and strategies for susceptibility variant discovery
Identification of common-variant associations for many common disorders has been highly effective, but the loci detected so far typically explain only a small proportion of the genetic predisposition to disease. Extending explained genetic variance is one of the major near-term goals of human geneti...
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| Formato: | Texto |
| Lenguaje: | English |
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BioMed Central
2009
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2717392/ https://www.ncbi.nlm.nih.gov/pubmed/19591663 http://dx.doi.org/10.1186/gm66 |