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Time course of angiopoietin-2 release during experimental human endotoxemia and sepsis

INTRODUCTION: Endothelial activation leading to vascular barrier breakdown denotes a devastating event in sepsis. Angiopoietin (Ang)-2, a circulating antagonistic ligand of the endothelial specific Tie2 receptor, is rapidly released from Weibel-Palade and has been identified as a non-redundant gatek...

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Detalles Bibliográficos
Autores principales:	Kümpers, Philipp, van Meurs, Matijs, David, Sascha, Molema, Grietje, Bijzet, Johan, Lukasz, Alexander, Biertz, Frank, Haller, Hermann, Zijlstra, Jan G
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2009
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2717419/ https://www.ncbi.nlm.nih.gov/pubmed/19416526 http://dx.doi.org/10.1186/cc7866

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