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Clinical Significance of Epigenetic Inactivation of hMLH1 and BRCA1 in Tunisian Patients with Invasive Breast Carcinoma

Aberrant hypermethylation of gene promoter regions is one of the mechanisms for inactivation of tumour suppressor genes in many human cancers including breast carcinoma. In the current study, we aimed to assess by MSP, the methylation pattern of two cancer-related genes involved in DNA repair: hMLH1...

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Detalles Bibliográficos
Autores principales:	Karray-Chouayekh, Sondes, Trifa, Fatma, Khabir, Abdelmajid, Boujelbane, Nouredine, Sellami-Boudawara, Tahia, Daoud, Jamel, Frikha, Mounir, Gargouri, Ali, Mokdad-Gargouri, Raja
Formato:	Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2009
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2717605/ https://www.ncbi.nlm.nih.gov/pubmed/19644562 http://dx.doi.org/10.1155/2009/369129

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