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Cohesin regulates VSG monoallelic expression in trypanosomes

Antigenic variation allows Trypanosoma brucei to evade the host immune response by switching the expression of 1 out of ∼15 telomeric variant surface glycoprotein (VSG) expression sites (ESs). VSG ES transcription is mediated by RNA polymerase I in a discrete nuclear site named the ES body (ESB). Ho...

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Detalles Bibliográficos
Autores principales: Landeira, David, Bart, Jean-Mathieu, Van Tyne, Daria, Navarro, Miguel
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2717648/
https://www.ncbi.nlm.nih.gov/pubmed/19635842
http://dx.doi.org/10.1083/jcb.200902119