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Mutations reveal voltage gating of CNGA1 channels in saturating cGMP
Activity of cyclic nucleotide–gated (CNG) cation channels underlies signal transduction in vertebrate visual receptors. These highly specialized receptor channels open when they bind cyclic GMP (cGMP). Here, we find that certain mutations restricted to the region around the ion selectivity filter re...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2009
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2717697/ https://www.ncbi.nlm.nih.gov/pubmed/19635856 http://dx.doi.org/10.1085/jgp.200910240 |