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Mutations reveal voltage gating of CNGA1 channels in saturating cGMP

Activity of cyclic nucleotide–gated (CNG) cation channels underlies signal transduction in vertebrate visual receptors. These highly specialized receptor channels open when they bind cyclic GMP (cGMP). Here, we find that certain mutations restricted to the region around the ion selectivity filter re...

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Detalles Bibliográficos
Autores principales:	Martínez-François, Juan Ramón, Xu, Yanping, Lu, Zhe
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2009
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2717697/ https://www.ncbi.nlm.nih.gov/pubmed/19635856 http://dx.doi.org/10.1085/jgp.200910240

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