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The Activation Of ATM Depends On Chromatin Interactions Occurring Prior To DNA-Damage Induction

Efficient and correct responses to double stranded breaks (DSB) in chromosomal DNA are critical for maintaining genomic stability and preventing chromosomal alterations leading to cancer1. The generation of DSB is associated with structural changes in chromatin and the activation of the protein kina...

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Detalles Bibliográficos
Autores principales:	Kim, Yong-Chul, Gerlitz, Gabi, Furusawa, Takashi, Catez, Frédéric, Nussenzweig, Andre, Oh, Kyu-Seon, Kraemer, Kenneth H., Shiloh, Yosef, Bustin, Michael
Formato:	Texto
Lenguaje:	English
Publicado:	2008
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2717731/ https://www.ncbi.nlm.nih.gov/pubmed/19079244 http://dx.doi.org/10.1038/ncb1817

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