Cargando…

PRL-3 overexpression in epithelial cells is induced by surrounding stromal fibroblasts

We isolate and culture carcinoma-associated fibroblasts (CAFs) from primary tumour (CAFpt), CAFs from corresponding synchronous liver metastasis (CAFlm) as well as normal colonic fibroblasts (NCF) from the same patient. From these cultures, conditioned media (CM) was obtained. Culture of a wide pane...

Descripción completa

Detalles Bibliográficos
Autores principales:	Molleví, David G, Aytes, Alvaro, Berdiel, Mireia, Padullés, Laura, Martínez-Iniesta, Maria, Sanjuan, Xavier, Salazar, Ramon, Villanueva, Alberto
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2009
Materias:	Short Communication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2717908/ https://www.ncbi.nlm.nih.gov/pubmed/19586538 http://dx.doi.org/10.1186/1476-4598-8-46

Ejemplares similares

PRL-3 is essentially overexpressed in primary colorectal tumours and associates with tumour aggressiveness
por: Molleví, D G, et al.
Publicado: (2008)

A 5-gene classifier from the carcinoma-associated fibroblast transcriptomic profile and clinical outcome in colorectal cancer
por: Berdiel-Acer, Mireia, et al.
Publicado: (2014)

Carcinoma-associated fibroblasts affect sensitivity to oxaliplatin and 5FU in colorectal cancer cells
por: Gonçalves-Ribeiro, Samuel, et al.
Publicado: (2016)

IFNβ1 secreted by breast cancer cells undergoing chemotherapy reprograms stromal fibroblasts to support tumour growth after treatment
por: Maia, Ana, et al.
Publicado: (2021)

Expression and prognostic impact of the protein tyrosine phosphatases PRL-1, PRL-2, and PRL-3 in breast cancer
por: Radke, I, et al.
Publicado: (2006)

PRL3-zumab as an immunotherapy to inhibit tumors expressing PRL3 oncoprotein
por: Thura, Min, et al.
Publicado: (2019)

Stromal NRG1 in luminal breast cancer defines pro-fibrotic and migratory cancer-associated fibroblasts
por: Berdiel-Acer, Mireia, et al.
Publicado: (2021)

PRL-3 disrupts epithelial architecture by altering the post-mitotic midbody position
por: Luján, Pablo, et al.
Publicado: (2016)

Overexpression of PRL7D1 in Leydig Cells Causes Male Reproductive Dysfunction in Mice
por: Liu, Yaping, et al.
Publicado: (2016)

Author Correction: PRL3-zumab as an immunotherapy to inhibit tumors expressing PRL3 oncoprotein
por: Thura, Min, et al.
Publicado: (2021)

Therapeutic potential of PRL-3 targeting and clinical significance of PRL-3 genomic amplification in gastric cancer
por: Ooki, Akira, et al.
Publicado: (2011)

Phosphatase of regenerating liver-3 (PRL-3) is overexpressed in classical Hodgkin lymphoma and promotes survival and migration
por: Hjort, Magnus Aassved, et al.
Publicado: (2018)

Analysis of molecular determinants of PRL-3
por: Pascaru, Mihaela, et al.
Publicado: (2009)

PRL3 induces polyploid giant cancer cells eliminated by PRL3-zumab to reduce tumor relapse
por: Thura, Min, et al.
Publicado: (2021)

Integrated Analysis of Global mRNA and Protein Expression Data in HEK293 Cells Overexpressing PRL-1
por: Dumaual, Carmen M., et al.
Publicado: (2013)

Phosphatase of regenerating liver 3 (PRL-3) is overexpressed in human prostate cancer tissue and promotes growth and migration
por: Vandsemb, Esten N., et al.
Publicado: (2016)

Pten in Stromal Fibroblasts Suppresses Mammary Epithelial Tumors
por: Trimboli, Anthony J., et al.
Publicado: (2009)

AKT in Stromal Fibroblasts Controls Invasion of Epithelial Cells
por: Cichon, Ann-Christin, et al.
Publicado: (2013)

Src-Mediated Phosphorylation of the Tyrosine Phosphatase PRL-3 Is Required for PRL-3 Promotion of Rho Activation, Motility and Invasion
por: Fiordalisi, James J., et al.
Publicado: (2013)

Depletion of Tissue-Specific Ion Transporters Causes Differential Expression of PRL Targets in Response to Increased Levels of Endogenous PRL
por: Shu, Tingting, et al.
Publicado: (2018)

MiR-130a-3p Inhibits PRL Expression and Is Associated With Heat Stress-Induced PRL Reduction
por: Zhang, Haojie, et al.
Publicado: (2020)

Generation of conditional knockout alleles for PRL-3()
por: Yan, Hong, et al.
Publicado: (2011)

Dysregulation of Mir-196b in Head and Neck Cancers Leads to Pleiotropic Effects in the Tumor Cells and Surrounding Stromal Fibroblasts
por: Álvarez-Teijeiro, Saúl, et al.
Publicado: (2017)

Author Correction: PRL3 induces polyploid giant cancer cells eliminated by PRL3-zumab to reduce tumor relapse
por: Thura, Min, et al.
Publicado: (2021)

Epithelial and stromal circadian clocks are inversely regulated by their mechano-matrix environment
por: Williams, Jack, et al.
Publicado: (2018)

Exploiting frequent and specific expression of PRL3 in pediatric solid tumors for first-in-child use of PRL3-zumab humanized antibody
por: Loh, Amos Hong Pheng, et al.
Publicado: (2023)

The pro-metastasis tyrosine phosphatase, PRL-3 (PTP4A3), is a novel mediator of oncogenic function of BCR-ABL in human chronic myeloid leukemia
por: Zhou, Jianbiao, et al.
Publicado: (2012)

Anti-cytomegalovirus activity of the anthraquinone atanyl blue PRL
por: Alam, Zohaib, et al.
Publicado: (2015)

Regulatory mechanisms of phosphatase of regenerating liver (PRL)-3
por: Rubio, Teresa, et al.
Publicado: (2016)

PRL-3 promotes telomere deprotection and chromosomal instability
por: Lian, Shenyi, et al.
Publicado: (2017)

Phosphatase, pseudo-phosphatase, or both? Understanding PRL oncogenicity
por: Gehring, Kalle, et al.
Publicado: (2020)

Binocularity Principles of PRL Development in Patients With Macular Disease
por: Tarita-Nistor, Luminita, et al.
Publicado: (2022)

Acceleration of Fracture Healing by Overexpression of Basic Fibroblast Growth Factor in the Mesenchymal Stromal Cells
por: Zhang, Hongliang, et al.
Publicado: (2017)

Cholesteatoma Fibroblasts Promote Epithelial Cell Proliferation through Overexpression of Epiregulin
por: Yoshikawa, Mamoru, et al.
Publicado: (2013)

PRL-1 overexpressed placenta-derived mesenchymal stem cells suppress adipogenesis in Graves’ ophthalmopathy through SREBP2/HMGCR pathway
por: Park, Mira, et al.
Publicado: (2021)

Production of Murine Leukemia RL♂1 Rejection Antigen Peptide pRL1a by Proteolysis of Natural Precursor pRL1b
por: Ono, Toshiro, et al.
Publicado: (1996)

Overexpression of thymic stromal lymphopoietin is correlated with poor prognosis in epithelial ovarian carcinoma
por: Xu, Lu, et al.
Publicado: (2019)

Optimizing a 3D Culture System to Study the Interaction between Epithelial Breast Cancer and Its Surrounding Fibroblasts
por: Li, Liyuan, et al.
Publicado: (2011)

Microplastics and anthropogenic fibre concentrations in lakes reflect surrounding land use
por: Tanentzap, Andrew J., et al.
Publicado: (2021)

PRL/microRNA-183/IRS1 Pathway Regulates Milk Fat Metabolism in Cow Mammary Epithelial Cells
por: Jiao, Peixin, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_ttu053gt54shmf1d6s4fa24orh