PR3-ANCA in Wegener's granulomatosis prime human mononuclear cells for enhanced activation via TLRs and NOD1/2

BACKGROUND: Anti-neutrophil cytoplasmic antibodies (ANCA) is autoantibodies characteristic of vasculitis diseases. A connection between ANCA and Wegener's granulomatosis was well established. The interaction of both ANCA phenotypes (PR3-ANCA and MPO-ANCA) with leukocytes provoked cell activatio...

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Detalles Bibliográficos
Autores principales: Uehara, Akiko, Sato, Tadasu, Iwashiro, Atsushi, Yokota, Sou
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2717921/
https://www.ncbi.nlm.nih.gov/pubmed/19594951
http://dx.doi.org/10.1186/1746-1596-4-23

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