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Mitogen-activated protein kinases and NFκB are involved in SP-A-enhanced responses of macrophages to mycobacteria

BACKGROUND: Surfactant protein A (SP-A) is a C-type lectin involved in surfactant homeostasis as well as host defense in the lung. We have recently demonstrated that SP-A enhances the killing of bacillus Calmette-Guerin (BCG) by rat macrophages through a nitric oxide-dependent pathway. In the curren...

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Detalles Bibliográficos
Autores principales: Lopez, Joseph P, Vigerust, David J, Shepherd, Virginia L
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2717924/
https://www.ncbi.nlm.nih.gov/pubmed/19566962
http://dx.doi.org/10.1186/1465-9921-10-60