DNA breaks as triggers for antigenic variation in African trypanosomes

The DNA repair machinery has been co-opted for antigenic variation in African trypanosomes. New work directly demonstrates that a double-strand break initiates a switch in the expressed variant surface coat.

Detalles Bibliográficos
Autores principales: Alsford, Sam, Horn, David, Glover, Lucy
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Minireview
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2718488/
https://www.ncbi.nlm.nih.gov/pubmed/19519956
http://dx.doi.org/10.1186/gb-2009-10-6-223
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author Alsford, Sam
Horn, David
Glover, Lucy
author_facet Alsford, Sam
Horn, David
Glover, Lucy
author_sort Alsford, Sam
collection PubMed
description The DNA repair machinery has been co-opted for antigenic variation in African trypanosomes. New work directly demonstrates that a double-strand break initiates a switch in the expressed variant surface coat.
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spelling pubmed-27184882010-06-08 DNA breaks as triggers for antigenic variation in African trypanosomes Alsford, Sam Horn, David Glover, Lucy Genome Biol Minireview The DNA repair machinery has been co-opted for antigenic variation in African trypanosomes. New work directly demonstrates that a double-strand break initiates a switch in the expressed variant surface coat. BioMed Central 2009 2009-06-08 /pmc/articles/PMC2718488/ /pubmed/19519956 http://dx.doi.org/10.1186/gb-2009-10-6-223 Text en Copyright © 2009 BioMed Central Ltd
spellingShingle Minireview
Alsford, Sam
Horn, David
Glover, Lucy
DNA breaks as triggers for antigenic variation in African trypanosomes
title DNA breaks as triggers for antigenic variation in African trypanosomes
title_full DNA breaks as triggers for antigenic variation in African trypanosomes
title_fullStr DNA breaks as triggers for antigenic variation in African trypanosomes
title_full_unstemmed DNA breaks as triggers for antigenic variation in African trypanosomes
title_short DNA breaks as triggers for antigenic variation in African trypanosomes
title_sort dna breaks as triggers for antigenic variation in african trypanosomes
topic Minireview
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2718488/
https://www.ncbi.nlm.nih.gov/pubmed/19519956
http://dx.doi.org/10.1186/gb-2009-10-6-223
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AT horndavid dnabreaksastriggersforantigenicvariationinafricantrypanosomes
AT gloverlucy dnabreaksastriggersforantigenicvariationinafricantrypanosomes

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