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DNA breaks as triggers for antigenic variation in African trypanosomes

The DNA repair machinery has been co-opted for antigenic variation in African trypanosomes. New work directly demonstrates that a double-strand break initiates a switch in the expressed variant surface coat.

Detalles Bibliográficos
Autores principales: Alsford, Sam, Horn, David, Glover, Lucy
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2718488/
https://www.ncbi.nlm.nih.gov/pubmed/19519956
http://dx.doi.org/10.1186/gb-2009-10-6-223