Insights into the regulation of intrinsically disordered proteins in the human proteome by analyzing sequence and gene expression data

BACKGROUND: Disordered proteins need to be expressed to carry out specified functions; however, their accumulation in the cell can potentially cause major problems through protein misfolding and aggregation. Gene expression levels, mRNA decay rates, microRNA (miRNA) targeting and ubiquitination have...

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Detalles Bibliográficos
Autores principales: Edwards, Yvonne JK, Lobley, Anna E, Pentony, Melissa M, Jones, David T
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2718516/
https://www.ncbi.nlm.nih.gov/pubmed/19432952
http://dx.doi.org/10.1186/gb-2009-10-5-r50

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