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Multi-tissue coexpression networks reveal unexpected subnetworks associated with disease
BACKGROUND: Obesity is a particularly complex disease that at least partially involves genetic and environmental perturbations to gene-networks connecting the hypothalamus and several metabolic tissues, resulting in an energy imbalance at the systems level. RESULTS: To provide an inter-tissue view o...
Autores principales: | Dobrin, Radu, Zhu, Jun, Molony, Cliona, Argman, Carmen, Parrish, Mark L, Carlson, Sonia, Allan, Mark F, Pomp, Daniel, Schadt, Eric E |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2718521/ https://www.ncbi.nlm.nih.gov/pubmed/19463160 http://dx.doi.org/10.1186/gb-2009-10-5-r55 |
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