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Aging and Environmental Exposures Alter Tissue-Specific DNA Methylation Dependent upon CpG Island Context

Epigenetic control of gene transcription is critical for normal human development and cellular differentiation. While alterations of epigenetic marks such as DNA methylation have been linked to cancers and many other human diseases, interindividual epigenetic variations in normal tissues due to agin...

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Detalles Bibliográficos
Autores principales:	Christensen, Brock C., Houseman, E. Andres, Marsit, Carmen J., Zheng, Shichun, Wrensch, Margaret R., Wiemels, Joseph L., Nelson, Heather H., Karagas, Margaret R., Padbury, James F., Bueno, Raphael, Sugarbaker, David J., Yeh, Ru-Fang, Wiencke, John K., Kelsey, Karl T.
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2009
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2718614/ https://www.ncbi.nlm.nih.gov/pubmed/19680444 http://dx.doi.org/10.1371/journal.pgen.1000602

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