Cargando…
The effectiveness of position- and composition-specific gap costs for protein similarity searches
Motivation: The flexibility in gap cost enjoyed by hidden Markov models (HMMs) is expected to afford them better retrieval accuracy than position-specific scoring matrices (PSSMs). We attempt to quantify the effect of more general gap parameters by separately examining the influence of position- and...
| Autores principales: | , , , |
|---|---|
| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2008
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2718649/ https://www.ncbi.nlm.nih.gov/pubmed/18586708 http://dx.doi.org/10.1093/bioinformatics/btn171 |