Swelfe: a detector of internal repeats in sequences and structures

Summary: Intragenic duplications of genetic material have important biological roles because of their protein sequence and structural consequences. We developed Swelfe to find internal repeats at three levels. Swelfe quickly identifies statistically significant internal repeats in DNA and amino acid...

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Detalles Bibliográficos
Autores principales: Abraham, Anne-Laure, Rocha, Eduardo P. C., Pothier, Joël
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2008
Materias:
Applications Note
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2718673/
https://www.ncbi.nlm.nih.gov/pubmed/18487242
http://dx.doi.org/10.1093/bioinformatics/btn234
Descripción
Sumario:Summary: Intragenic duplications of genetic material have important biological roles because of their protein sequence and structural consequences. We developed Swelfe to find internal repeats at three levels. Swelfe quickly identifies statistically significant internal repeats in DNA and amino acid sequences and in 3D structures using dynamic programming. The associated web server also shows the relationships between repeats at each level and facilitates visualization of the results. Availability: http://bioserv.rpbs.jussieu.fr/swelfe Contact: annela@abi.snv.jussieu.fr Supplementary information: Supplementary data are available at Bioinformatics online.

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