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Swelfe: a detector of internal repeats in sequences and structures

Summary: Intragenic duplications of genetic material have important biological roles because of their protein sequence and structural consequences. We developed Swelfe to find internal repeats at three levels. Swelfe quickly identifies statistically significant internal repeats in DNA and amino acid...

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Detalles Bibliográficos
Autores principales: Abraham, Anne-Laure, Rocha, Eduardo P. C., Pothier, Joël
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2718673/
https://www.ncbi.nlm.nih.gov/pubmed/18487242
http://dx.doi.org/10.1093/bioinformatics/btn234
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author Abraham, Anne-Laure
Rocha, Eduardo P. C.
Pothier, Joël
author_facet Abraham, Anne-Laure
Rocha, Eduardo P. C.
Pothier, Joël
author_sort Abraham, Anne-Laure
collection PubMed
description Summary: Intragenic duplications of genetic material have important biological roles because of their protein sequence and structural consequences. We developed Swelfe to find internal repeats at three levels. Swelfe quickly identifies statistically significant internal repeats in DNA and amino acid sequences and in 3D structures using dynamic programming. The associated web server also shows the relationships between repeats at each level and facilitates visualization of the results. Availability: http://bioserv.rpbs.jussieu.fr/swelfe Contact: annela@abi.snv.jussieu.fr Supplementary information: Supplementary data are available at Bioinformatics online.
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spelling pubmed-27186732009-07-31 Swelfe: a detector of internal repeats in sequences and structures Abraham, Anne-Laure Rocha, Eduardo P. C. Pothier, Joël Bioinformatics Applications Note Summary: Intragenic duplications of genetic material have important biological roles because of their protein sequence and structural consequences. We developed Swelfe to find internal repeats at three levels. Swelfe quickly identifies statistically significant internal repeats in DNA and amino acid sequences and in 3D structures using dynamic programming. The associated web server also shows the relationships between repeats at each level and facilitates visualization of the results. Availability: http://bioserv.rpbs.jussieu.fr/swelfe Contact: annela@abi.snv.jussieu.fr Supplementary information: Supplementary data are available at Bioinformatics online. Oxford University Press 2008-07-01 2008-05-16 /pmc/articles/PMC2718673/ /pubmed/18487242 http://dx.doi.org/10.1093/bioinformatics/btn234 Text en © 2008 The Author(s) http://creativecommons.org/licenses/by-nc/2.0/uk/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/2.0/uk/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Applications Note
Abraham, Anne-Laure
Rocha, Eduardo P. C.
Pothier, Joël
Swelfe: a detector of internal repeats in sequences and structures
title Swelfe: a detector of internal repeats in sequences and structures
title_full Swelfe: a detector of internal repeats in sequences and structures
title_fullStr Swelfe: a detector of internal repeats in sequences and structures
title_full_unstemmed Swelfe: a detector of internal repeats in sequences and structures
title_short Swelfe: a detector of internal repeats in sequences and structures
title_sort swelfe: a detector of internal repeats in sequences and structures
topic Applications Note
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2718673/
https://www.ncbi.nlm.nih.gov/pubmed/18487242
http://dx.doi.org/10.1093/bioinformatics/btn234
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