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Nuclear Calcium Signaling Controls Expression of a Large Gene Pool: Identification of a Gene Program for Acquired Neuroprotection Induced by Synaptic Activity

Synaptic activity can boost neuroprotection through a mechanism that requires synapse-to-nucleus communication and calcium signals in the cell nucleus. Here we show that in hippocampal neurons nuclear calcium is one of the most potent signals in neuronal gene expression. The induction or repression...

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Detalles Bibliográficos
Autores principales: Zhang, Sheng-Jia, Zou, Ming, Lu, Li, Lau, David, Ditzel, Désirée A. W., Delucinge-Vivier, Celine, Aso, Yoshinori, Descombes, Patrick, Bading, Hilmar
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2718706/
https://www.ncbi.nlm.nih.gov/pubmed/19680447
http://dx.doi.org/10.1371/journal.pgen.1000604