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Plasmodium falciparum–Mediated Induction of Human CD25(hi)Foxp3(hi) CD4 T Cells Is Independent of Direct TCR Stimulation and Requires IL-2, IL-10 and TGFβ

CD4(+)CD25(+)Foxp3(+) regulatory T cells (Tregs) regulate disease-associated immunity and excessive inflammatory responses, and numbers of CD4(+)CD25(+)Foxp3(+) Tregs are increased during malaria infection. The mechanisms governing their generation, however, remain to be elucidated. In this study we...

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Detalles Bibliográficos
Autores principales:	Scholzen, Anja, Mittag, Diana, Rogerson, Stephen J., Cooke, Brian M., Plebanski, Magdalena
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2009
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2718810/ https://www.ncbi.nlm.nih.gov/pubmed/19680449 http://dx.doi.org/10.1371/journal.ppat.1000543

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