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Mycobacterium tuberculosis WhiB3 Maintains Redox Homeostasis by Regulating Virulence Lipid Anabolism to Modulate Macrophage Response
The metabolic events associated with maintaining redox homeostasis in Mycobacterium tuberculosis (Mtb) during infection are poorly understood. Here, we discovered a novel redox switching mechanism by which Mtb WhiB3 under defined oxidizing and reducing conditions differentially modulates the assimil...
Autores principales: | Singh, Amit, Crossman, David K., Mai, Deborah, Guidry, Loni, Voskuil, Martin I., Renfrow, Matthew B., Steyn, Adrie J. C. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2718811/ https://www.ncbi.nlm.nih.gov/pubmed/19680450 http://dx.doi.org/10.1371/journal.ppat.1000545 |
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