Challenging complications of treatment – human herpes virus 6 encephalitis and pneumonitis in a patient undergoing autologous stem cell transplantation for relapsed Hodgkin's disease: a case report

BACKGROUND: Reactivation of human herpesvirus 6 (HHV-6) occurs frequently in patients after allogeneic stem cell transplantation and is associated with bone-marrow suppression, enteritis, pneumonitis, pericarditis and also encephalitis. After autologous stem cell transplantation or intensive polyche...

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Autores principales: Bommer, Martin, Pauls, Sandra, Greiner, Jochen
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2718875/
https://www.ncbi.nlm.nih.gov/pubmed/19619326
http://dx.doi.org/10.1186/1743-422X-6-111
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author Bommer, Martin
Pauls, Sandra
Greiner, Jochen
author_facet Bommer, Martin
Pauls, Sandra
Greiner, Jochen
author_sort Bommer, Martin
collection PubMed
description BACKGROUND: Reactivation of human herpesvirus 6 (HHV-6) occurs frequently in patients after allogeneic stem cell transplantation and is associated with bone-marrow suppression, enteritis, pneumonitis, pericarditis and also encephalitis. After autologous stem cell transplantation or intensive polychemotherapy HHV-6 reactivation is rarely reported. CASE REPORT: This case demonstrates a severe symptomatic HHV-6 infection with encephalitis and pneumonitis after autologous stem cell transplantation of a patient with relapsed Hodgkin's disease. CONCLUSION: Careful diagnostic work up in patients with severe complications after autologous stem cell transplantation is mandatory to identify uncommon infections.
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spelling pubmed-27188752009-07-31 Challenging complications of treatment – human herpes virus 6 encephalitis and pneumonitis in a patient undergoing autologous stem cell transplantation for relapsed Hodgkin's disease: a case report Bommer, Martin Pauls, Sandra Greiner, Jochen Virol J Case Report BACKGROUND: Reactivation of human herpesvirus 6 (HHV-6) occurs frequently in patients after allogeneic stem cell transplantation and is associated with bone-marrow suppression, enteritis, pneumonitis, pericarditis and also encephalitis. After autologous stem cell transplantation or intensive polychemotherapy HHV-6 reactivation is rarely reported. CASE REPORT: This case demonstrates a severe symptomatic HHV-6 infection with encephalitis and pneumonitis after autologous stem cell transplantation of a patient with relapsed Hodgkin's disease. CONCLUSION: Careful diagnostic work up in patients with severe complications after autologous stem cell transplantation is mandatory to identify uncommon infections. BioMed Central 2009-07-20 /pmc/articles/PMC2718875/ /pubmed/19619326 http://dx.doi.org/10.1186/1743-422X-6-111 Text en Copyright © 2009 Bommer et al; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License ( (http://creativecommons.org/licenses/by/2.0) ), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Bommer, Martin
Pauls, Sandra
Greiner, Jochen
Challenging complications of treatment – human herpes virus 6 encephalitis and pneumonitis in a patient undergoing autologous stem cell transplantation for relapsed Hodgkin's disease: a case report
title Challenging complications of treatment – human herpes virus 6 encephalitis and pneumonitis in a patient undergoing autologous stem cell transplantation for relapsed Hodgkin's disease: a case report
title_full Challenging complications of treatment – human herpes virus 6 encephalitis and pneumonitis in a patient undergoing autologous stem cell transplantation for relapsed Hodgkin's disease: a case report
title_fullStr Challenging complications of treatment – human herpes virus 6 encephalitis and pneumonitis in a patient undergoing autologous stem cell transplantation for relapsed Hodgkin's disease: a case report
title_full_unstemmed Challenging complications of treatment – human herpes virus 6 encephalitis and pneumonitis in a patient undergoing autologous stem cell transplantation for relapsed Hodgkin's disease: a case report
title_short Challenging complications of treatment – human herpes virus 6 encephalitis and pneumonitis in a patient undergoing autologous stem cell transplantation for relapsed Hodgkin's disease: a case report
title_sort challenging complications of treatment – human herpes virus 6 encephalitis and pneumonitis in a patient undergoing autologous stem cell transplantation for relapsed hodgkin's disease: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2718875/
https://www.ncbi.nlm.nih.gov/pubmed/19619326
http://dx.doi.org/10.1186/1743-422X-6-111
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AT greinerjochen challengingcomplicationsoftreatmenthumanherpesvirus6encephalitisandpneumonitisinapatientundergoingautologousstemcelltransplantationforrelapsedhodgkinsdiseaseacasereport

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