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Impact of the TCR Signal on Regulatory T Cell Homeostasis, Function, and Trafficking
Signaling through the T cell antigen receptor (TCR) is important for the homeostasis of naïve and memory CD4(+) T cells. The significance of TCR signaling in regulatory T (Treg) cells has not been systematically addressed. Using an Ox40-cre allele that is prominently expressed in Treg cells, and a c...
Autores principales: | Kim, Joong Kyu, Klinger, Mark, Benjamin, Jonathan, Xiao, Yuanyuan, Erle, David J., Littman, Dan R., Killeen, Nigel |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2719063/ https://www.ncbi.nlm.nih.gov/pubmed/19668367 http://dx.doi.org/10.1371/journal.pone.0006580 |
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